Zinc and Zinc Transporters in Normal Prostate Function and the Pathogenesis of Prostate Cancer
نویسندگان
چکیده
1. Abstract 2. Introduction 3. Zinc levels in normal human prostate 4. Zinc import into prostate cells 4.1. Zinc uptake transporters 4.2. Zinc import into mitochondria 5. Effects of zinc accumulation on prostate cells 5.1. Zinc and net citrate production 5.2. Zinc and terminal oxidation 5.3. Zinc effects on mitochondrial apoptogenesis 5.4. The effect of zinc on the bioenergetics of the prostate cell 6. Hormone regulation of zinc in the prostate 7. Altered zinc and citrate-related metabolism in prostate cancer 8. Conclusions and perspective 9. Acknowledgement 10. References
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